Laxatives

In Australia, as in many other countries, a variety of laxative classes are available, each with different mechanisms of action. Here’s an overview of these classes, including examples of both generic and brand names:

  1. Bulk-Forming Laxatives
    1. Mechanism of Action: These laxatives increase fecal bulk by absorbing water, which stimulates bowel movement.
    2. Examples:
      1. Psyllium (Metamucil®)
      2. Ispaghula husk (Fybogel®)
  2. Osmotic Laxatives
    1. Mechanism of Action: They work by drawing water into the bowel from the surrounding body tissues, softening stools and increasing bowel movements.
    2. Examples:
      1. Macrogol (Movicol®)
      2. Lactulose (Actilax®, Duphalac®)
  3. Stimulant Laxatives
    1. Mechanism of Action: These laxatives increase bowel movements by stimulating the nerve endings in the large intestine.
    2. Examples:
      1. Senna (Senokot®)
      2. Bisacodyl (Dulcolax®)
  4. Stool Softeners
    1. Mechanism of Action: They work by softening the stool, making it easier to pass.
    2. Examples:
      1. Docusate sodium (Coloxyl®)
  5. Lubricant Laxatives
    1. Mechanism of Action: These laxatives coat the stool and the lining of the gut with a slippery film, which helps the stool to move through the gut more easily.
    2. Examples:
      1. Mineral oil (available under various brand names)
  6. Saline Laxatives
    1. Mechanism of Action: They increase the amount of water in the intestines, which softens the stool and stimulates bowel movements.
    2. Examples:
      1. Magnesium sulfate (Epsom salts)
      2. Magnesium hydroxide (Milk of Magnesia)
  7. General
    1. Individual Responses Vary: Not all laxatives work the same for everyone, and a trial-and-error approach is often needed.
    2. Medical Advice: It’s important for patient to consult a healthcare provider before starting any laxative, especially if they have underlying health conditions or are taking other medications.
    3. Long-Term Use Caution: Prolonged use of certain laxatives, especially stimulant laxatives, can lead to dependence and might be harmful.