Here is a list of drugs that can cause hyponatremia:
- Diuretics
- Thiazides
- Hydrochlorothiazide (e.g., Hygroton, Dithiazide)
- Indapamide (e.g., Natrilix, Lozide)
- Loop Diuretics
- Furosemide (Frusemide) (e.g., Lasix, Frusemide Sandoz)
- Bumetanide (e.g., Burinex)
- Thiazides
- Selective Serotonin Reuptake Inhibitors (SSRIs)
- Fluoxetine (e.g., Prozac, Lovan)
- Sertraline (e.g., Zoloft, Sertra)
- Citalopram (e.g., Cipramil, Talohexal)
- Escitalopram (e.g., Lexapro, Esipram)
- Paroxetine (e.g., Aropax, Paxtine)
- Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs)
- Venlafaxine (e.g., Effexor XR, Enlafax)
- Duloxetine (e.g., Cymbalta, Duonex)
- Tricyclic Antidepressants
- Amitriptyline (e.g., Endep, Tryptanol)
- Nortriptyline (e.g., Allegron)
- Imipramine (e.g., Tofranil, Deptran)
- Antiepileptics
- Carbamazepine (e.g., Tegretol, Teril)
- Oxcarbazepine (e.g., Trileptal, Oxtellar XR)
- Antipsychotics
- Clozapine (e.g., Clozaril, Alemoxan)
- Olanzapine (e.g., Zyprexa, Olanzane)
- Mood Stabilizers
- Lithium (e.g., Lithicarb, Quilonum)
- Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
- Ibuprofen (e.g., Nurofen, Brufen)
- Naproxen (e.g., Naprosyn, Inza)
- Celecoxib (e.g., Celebrex, Cobix)
- Angiotensin II Receptor Blockers (ARBs) and Angiotensin-Converting Enzyme (ACE) Inhibitors
- ARBs: Losartan (e.g., Cozaar, Losartas), Candesartan (e.g., Atacand, Amias)
- ACE Inhibitors: Enalapril (e.g., Renitec, Enapril), Ramipril (e.g., Tritace, Ramace)
- Vasopressin Analogues and Antagonists
- Desmopressin (e.g., Minirin, DDAVP)
- Ecstasy (MDMA)
- Not a prescription medication, but notable for its potential to cause severe hyponatremia.
- Chemotherapy Agents
- Cyclophosphamide (e.g., Endoxan, Cycloblastin)
Remember that the occurrence of hyponatremia depends on various factors including dosage, patient characteristics, and other concurrent medications. Regular monitoring and clinical assessment are key in managing patients on these medications.