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- Vascular
- Infections
- HIV infection
- Hepatitis C
- Creutzfeldt–Jakob disease
- Neurosyphilis
- Neoplastic
- Space occupying lesion; intracranial lesion; brain tumour
- Deficiencies
- Congenital
- Acute intermittent porphyria
- Autoimmune
- Systemic lupus erythematosus
- Toxins
- Heavy metal toxicities
- Wilson disease
- Endocrine
- Hypoglycaemia; hyperglycaemia; diabetes mellitus
- Cushing disease; pituitary adenoma
- Thyrotoxicosis; hyperthyroidism
- Hypothyroidism; myxoedema
- Hyperparathyroidism
- Addison disease
- Metabolic
- Electrolyte abnormality
- Metabolic abnormality
- Sleep deprivation
- Neurolopsychiatric
- Space occupying lesion
- Multiple sclerosis
- CVA