Non-Compliance with Medication

  • Fear:
    • patients may be frightened of potential side effects; they may have witnessed side effects experienced by someone else who was taking the same, or a similar, medication and believe the medication caused the problems
  • Side Effects:
    • patients may attribute side effects of one medication to a number of medications and cease taking them all
  • Cost:
    • patients may not fill medications initially or ration what they do fill to extend their supply
  • Misunderstanding:
    • patients may not understand the need for the medication, the nature of the side effects or the time it will take to see positive results; failure to see immediate improvement may lead to premature discontinuation
  • Too many medications:
    • the greater the number of different medications prescribed and the higher the dosing frequency, the more likely a patient is to be non-adherent
  • Lack of symptoms:
    • patients who do not feel any differently when they start or stop their medication might see no reason to take it
  • Worry:
    • concerns about becoming dependent on medication can also lead to non-adherence
  • Depression:
    • patients who are depressed are less likely to take their medications as prescribed
  • Mistrust:
    • patients may be suspicious of their doctor’s motives for prescribing certain medications because of media coverage and pharmaceutical companies’ influence on prescribing patterns
  • Belief Systems:
    • a belief that prescription medications are toxic and are not natural may lead to trials of complementary medications.

To address non-compliance

  • Patient Education
  • Shared decision making
  • Pharmacist support
  • Motivational interviewing
  • Blister packs