Examination – Cognitive Decline


When a General Practitioner (GP) suspects cognitive decline in a patient, the assessment process generally involves the following steps:

  1. Patient History:
    • The GP will first ask the patient about their symptoms, including any changes in memory, thinking, behavior, or ability to perform daily tasks.
    • They will inquire about the onset, frequency, and progression of these symptoms.
    • They may also ask about medical history, medications, lifestyle factors, and family history of dementia or cognitive disorders.
  2. Family/Caregiver Interview:
    • Often, the patient may not be fully aware of their cognitive decline, so interviewing family members or caregivers can provide important additional insights into the patient’s behavior and functional abilities.
  3. Physical Examination:
    • The GP will conduct a general physical exam to check for signs that may be related to cognitive decline, such as cardiovascular disease, neurological deficits, or nutritional deficiencies.
  4. Cognitive Testing:
    • Various cognitive tests can help assess different areas of cognitive function.
    • These include clock drawing, the MMSE, GPCOG, RUDAS, MoCA and GDS (discussed below).
  5. Laboratory Tests:
    • Blood tests may be ordered to rule out other conditions that can cause cognitive impairment, like vitamin deficiencies (e.g., B12), thyroid dysfunction, or infections.
  6. Neuroimaging:
    • If warranted, imaging studies like CT or MRI scans can be used to rule out structural brain abnormalities, such as tumors, strokes, or hydrocephalus, which could be contributing to the cognitive decline.
  7. Referral to Specialists:
    • If the initial assessment suggests significant cognitive impairment or an unclear diagnosis, the GP may refer the patient to specialists like neurologists, geriatricians, or neuropsychologists for more comprehensive evaluation.
  8. Follow-Up and Management Plan:
    • The GP will develop a management plan based on the assessment findings.
    • This may include treatment for underlying conditions, lifestyle recommendations, and ongoing monitoring of the patient’s cognitive health.
    • In some cases, medications may be prescribed to slow the progression of certain types of dementia.
  9. Support Services:
    • Providing information on community support services, therapy, and caregiver resources may also be part of the management plan.

Cognitive Testing

  • Mini-Mental State Examination (MMSE):
    • This is one of the most commonly used tools for assessing cognitive impairment.
    • The MMSE evaluates several cognitive domains, including orientation to time and place, immediate recall, short-term memory, language use, comprehension, and basic motor skills.
    • Scores range from 0 to 30, with lower scores indicating more severe cognitive impairment.
  • Clock Drawing Test:
    • This test is used to assess visual-spatial abilities and executive function.
    • The patient is asked to draw a clock showing a specified time, typically “ten past eleven.”
    • Assessment focuses on the correct placement of the hands and numbers and the overall appearance of the clock.
  • Maze Test:
    • The Maze Test was developed as a pencil and paper test of attention, visuoconstructional ability, and executive functions of planning and foresight.
    • The participants compete a simple demonstration maze first in order to establish the rule set, then complete the Maze Task.
  • General Practitioner Assessment of Cognition (GPCOG):
    • The GPCOG is a screening tool specifically designed for use in primary care.
    • It includes a patient assessment, which tests memory and recall, and an informant interview, which asks a relative or close contact about changes in the patient’s cognitive and daily functioning.
    • GPCOG is available in many different languages.
  • Rowland Universal Dementia Assessment Scale (RUDAS):
    • This is a brief neurocognitive assessment designed to minimize cultural and educational bias, making it particularly useful in diverse populations.
    • It tests multiple cognitive domains, including memory, visuospatial orientation, praxis (motor planning), and executive function.
  • Montreal Cognitive Assessment (MoCA):
    • Similar to the MMSE but more sensitive in detecting mild cognitive impairment.
    • The MoCA evaluates several areas of cognitive function, including short-term memory recall, visuospatial abilities, executive functions, attention, concentration, language, and orientation to time and place.
  • Geriatric Depression Scale (GDS):
    • This is a self-report measure used to identify depression in the elderly.
    • Unlike other scales that assess mood, the GDS is designed to be simpler and less reliant on somatic symptoms, which can overlap with other illnesses in elderly populations.

MMSE

Maze Test

GPCOG

RUDAS

MoCA

GDS