CASE INFORMATION
Case ID: GPCCE-2025-01
Case Name: John Harrison
Age: 58
Gender: Male
Indigenous Status: Non-Indigenous
Year: 2025
ICPC-2 Codes:
- B83 – Abnormal blood test NOS
- B70 – Anaemia
- B80 – Iron deficiency anaemia
- B82 – Vitamin B12/folate deficiency anaemia
- B72 – Lymphadenitis NOS
COMPETENCY OUTCOMES
Competency Domain | Competency Element |
---|---|
1. Communication and Consultation Skills | 1.1 Communication is appropriate to the person and the sociocultural context. 1.2 Engages the patient to gather information about their symptoms, ideas, concerns, expectations of healthcare and the full impact of their illness experience on their lives. 1.4 Communicates effectively in routine and difficult situations. |
2. Clinical Information Gathering and Interpretation | 2.1 Gathers and interprets information about health needs, including the patient’s life stage and context. |
3. Diagnosis, Decision-Making and Reasoning | 3.1 Generates and prioritises hypotheses about health needs. 3.2 Demonstrates diagnostic reasoning and clinical judgement. |
4. Clinical Management and Therapeutic Reasoning | 4.1 Develops and implements patient-centred management plans. 4.2 Applies evidence-based medicine and shared decision-making. |
5. Preventive and Population Health | 5.1 Provides health promotion and disease prevention strategies. |
6. Professionalism | 6.1 Adheres to ethical, legal, and professional standards. |
7. General Practice Systems and Regulatory Requirements | 7.1 Practices within the Australian health care system and understands referral pathways. |
9. Managing Uncertainty | 9.1 Manages uncertainty and risk in decision-making. |
10. Identifying and Managing the Patient with Significant Illness | 10.1 Recognises and responds to potentially life-threatening conditions. |
CASE FEATURES
- Risk factors: age, family history of bowel cancer, previous smoker
- 58-year-old male presenting after abnormal routine blood tests
- Symptomless but fatigued and concerned about recent weight loss
- Iron deficiency anaemia on initial tests
- Low ferritin, low Hb, high RDW
- No overt gastrointestinal symptoms
INSTRUCTIONS
Review the following patient record summary and scenario.
Your examiner will ask you a series of questions based on this information.
You have 15 minutes to complete this case.
The time for each question will be managed by the examiner.
The time allocation for each question is roughly as follows:
- Question 1 – 3 minutes
- Question 2 – 3 minutes
- Question 3 – 3 minutes
- Question 4 – 3 minutes
- Question 5 – 3 minutes
PATIENT RECORD SUMMARY
Patient Details
Name: John Harrison
Age: 58
Gender: Male
Gender Assigned at Birth: Male
Indigenous Status: Non-Indigenous
Allergies and Adverse Reactions
- Nil known
Medications
- Ramipril 5 mg daily (for hypertension)
Past History
- Hypertension (diagnosed 5 years ago)
- Appendectomy (age 25)
- Ex-smoker (quit 8 years ago; 20 pack-years)
Social History
- Lives with wife
- Two adult children
- Retired schoolteacher
- Occasionally drinks alcohol (2–4 standard drinks on weekends)
- No illicit drug use
Family History
- Father: bowel cancer (diagnosed at age 62)
- Mother: type 2 diabetes
- Sister: rheumatoid arthritis
Smoking
- Ex-smoker (ceased 8 years ago)
Alcohol
- Drinks socially
Vaccination and Preventative Activities
- Up-to-date with immunisations
- Last colonoscopy: never
- No FOBT screening
SCENARIO
John Harrison presents for review of his routine health check blood tests.
He is asymptomatic except for mild fatigue over the past three months, which he attributes to “getting older.”
No other significant symptoms: denies rectal bleeding, changes in bowel habits, weight loss (but wife mentions his pants seem looser).
He is concerned because his father died of bowel cancer at 65.
He wants to know if anything serious is going on.
EXAMINATION FINDINGS
General Appearance: Alert, slightly pale
Temperature: 36.5°C
Blood Pressure: 128/78 mmHg
Heart Rate: 84 bpm, regular
Respiratory Rate: 14/min
Oxygen Saturation: 98% on room air
BMI: 23
Other examination findings:
- Conjunctival pallor
- No lymphadenopathy
- No abdominal masses or tenderness
- No hepatosplenomegaly
- PR exam not done
INVESTIGATION FINDINGS
Blood Results:
- WBC, Platelets, LFTs, UEC: Normal
- Hb: 98 g/L (130–180 g/L)
- MCV: 75 fL (80–100 fL)
- Ferritin: 6 µg/L (20–300 µg/L)
- Serum iron: 5 µmol/L (10–30 µmol/L)
- TIBC: 68 µmol/L (50–80 µmol/L)
- RDW: 18% (11.5–14.5%)
THE COMPETENT CANDIDATE
The competent candidate should be able to:
Q1: What is your diagnosis and differential diagnosis for John’s abnormal blood tests?
Answer:
The primary diagnosis is iron deficiency anaemia (IDA). This is based on the low haemoglobin (Hb 98 g/L), microcytic indices (MCV 75 fL), low ferritin (6 µg/L), low serum iron, and elevated red cell distribution width (RDW 18%). In adult males, iron deficiency anaemia is pathological until proven otherwise.
Differential Diagnoses:
- Iron Deficiency Anaemia (likely due to chronic blood loss—GIT malignancy or other causes)
- Anaemia of Chronic Disease (but ferritin is typically normal or elevated in ACD)
- Thalassaemia trait (unlikely with no family history and the absence of hypochromia/target cells on smear; also, normal RBC count)
- Lead poisoning (unlikely in this age/context)
- Vitamin B12/Folate deficiency (usually macrocytic, but mixed anaemia can be microcytic)
In this context, the leading differential is gastrointestinal blood loss due to a possible colorectal malignancy, especially given his age and positive family history.
Red Flags:
- Male gender with IDA
- Family history of bowel cancer
- Subtle weight loss (as reported by his wife)
- No prior screening (no FOBT or colonoscopy)
Q2: How would you further investigate the cause of John’s iron deficiency anaemia?
Answer:
Step 1: Gastrointestinal Investigations
- Colonoscopy: To rule out colorectal cancer or polyps
- Gastroscopy: To evaluate for upper GI bleeding, including peptic ulcers, gastric cancer, or coeliac disease
Step 2: Additional Blood Tests
- Coeliac serology (tTG-IgA and total IgA) to rule out coeliac disease as a cause of malabsorption
- Faecal occult blood test (FOBT) (although colonoscopy is more definitive)
Step 3: Other Investigations
- Urinalysis (to rule out haematuria)
- Stool examination (if indicated) for parasites (unlikely in this case)
Referrals:
- Gastroenterologist for upper and lower endoscopy
- Dietitian if malabsorption is diagnosed
Q3: What is your initial management plan while awaiting investigations?
Answer:
Immediate Plan:
- Start oral iron replacement (e.g., ferrous sulfate 325 mg daily or alternate days, depending on tolerance)
- Advise on dietary iron intake (red meats, leafy greens, legumes) and vitamin C to enhance absorption
- Counsel on potential side effects (constipation, GI upset)
Monitoring:
- Recheck Hb and ferritin in 2-4 weeks to assess response
- If no improvement or intolerance, consider IV iron
Addressing Concerns:
- Acknowledge his anxiety about cancer; explain the rationale for investigations
- Reassure that finding the cause early improves outcomes
- Emphasise a structured approach—we need to identify the source to treat appropriately
Q4: How would you communicate the need for further investigations, including invasive procedures, to John?
Answer:
- Use empathetic, clear communication; validate his concerns
- Explain the findings: “Your iron levels are low, and this is not normal in men. It can signal internal bleeding, often from the gut.”
- Discuss that a colonoscopy and gastroscopy are the gold standards for finding a cause
- Frame positively: “These tests can help detect and prevent serious disease early.”
- Use shared decision-making: involve him in choices, offer support
- Provide written information, answer all questions
- Offer a support person for his appointments if he wishes
Q5: What preventive health strategies should you discuss with John at this visit?
Answer:
- Colorectal cancer screening: Discuss routine screening starting at age 50, or earlier if high risk (as in his case)
- Cardiovascular risk management: BP well controlled, but assess lipids, blood glucose, BMI, and physical activity
- Vaccination: Ensure he is up to date with influenza, pneumococcal, and COVID-19 vaccines, given his age
- Smoking: Reaffirm cessation (he is an ex-smoker)
- Alcohol: Discuss alcohol intake and ensure it is within NHMRC guidelines
- Diet and Exercise: Promote a Mediterranean diet, regular exercise (150 mins/week)
- Mental health: Offer support or referral if he expresses anxiety related to his health status
SUMMARY OF A COMPETENT ANSWER
- Identifies iron deficiency anaemia in a male as a red flag requiring urgent investigation
- Prioritises colorectal cancer as a potential cause
- Requests gastroscopy and colonoscopy with appropriate referrals
- Initiates iron replacement therapy while awaiting investigations
- Communicates clearly and empathetically, addressing concerns about cancer
- Incorporates preventive health strategies (screening, vaccinations, lifestyle)
PITFALLS
- Failing to recognise the significance of IDA in men
- Delaying investigation for GI malignancy
- Neglecting to order both upper and lower GI evaluations
- Inadequate communication about invasive investigations
- Overlooking preventive health opportunities (screening, vaccinations)
REFERENCES
- RACGP Red Book (9th Edition)
- Cancer Council Australia on Colorectal Cancer Guidelines
- National Institutes of Health on Anaemia
MARKING
Each competency area is on the following scale from 0 to 3.
☐ Competency NOT demonstrated
☐ Competency NOT CLEARLY demonstrated
☐ Competency SATISFACTORILY demonstrated
☐ Competency FULLY demonstrated
1. Communication and Consultation Skills
1.1 Communication is appropriate to the person and the sociocultural context
1.2 Engages the patient to gather information about their symptoms, ideas, concerns, expectations of healthcare and the full impact of their illness experience on their lives
1.4 Communicates effectively in routine and difficult situations
2. Clinical Information Gathering and Interpretation
2.1 Gathers and interprets information about health needs, including the patient’s life stage and context
3. Diagnosis, Decision-Making and Reasoning
3.1 Generates and prioritises hypotheses about health needs
3.2 Demonstrates diagnostic reasoning and clinical judgement
4. Clinical Management and Therapeutic Reasoning
4.1 Develops and implements patient-centred management plans
4.2 Applies evidence-based medicine and shared decision-making
5. Preventive and Population Health
5.1 Provides health promotion and disease prevention strategies
6. Professionalism
6.1 Adheres to ethical, legal, and professional standards
7. General Practice Systems and Regulatory Requirements
7.1 Practices within the Australian health care system and understands referral pathways
9. Managing Uncertainty
9.1 Manages uncertainty and risk in decision-making
10. Identifying and Managing the Patient with Significant Illness
10.1 Recognises and responds to potentially life-threatening conditions
Competency at Fellowship Level
☐ CLEARLY BELOW STANDARD
☐ BELOW EXPECTED STANDARD
☐ BORDERLINE
☐ AT EXPECTED STANDARD
☐ ABOVE STANDARD